Don’t let knee pain keep you from your life. With a single injection, Monovisc provides long-lasting pain relief from knee pain.2

Sport Injury


Osteoarthritis affects 1 in 11 Australians. It develops in the joints, often involving the hips, knees, neck or small joints of the hands, and can cause stiffness and pain in the affected joints.1

It is the leading cause of musculoskeletal pain and disability.

The main symptoms of osteoarthritis are pain, stiffness and limited joint movement. At first pain is felt during and after activity, but as the condition worsens pain may be felt during minor movements or even at rest.1

Knee Joint


Viscosupplement injections replace lost joint fluid in osteoarthritis, improving mobility and relieving pain.

Monovisc is a single injection viscosupplement, providing long-lasting pain relief for the treatment of osteoarthritis.2,4

Viscosupplementation is most commonly used to treat the symptoms of knee osteoarthritis. These symptoms are typically pain and stiffness. Typical candidates for viscosupplements are people with osteoarthritis that have failed with other non-surgical treatments.3

Call center operators

Order Now

If you have been referred to this website by an authorised medical practitioner, you can order Monovisc today. Call our friendly customer service team on 1300 852 172 to place your order.

Osteoarthritis Knee Pain

Knee pain is a common problem experienced by people of all ages. It can occur suddenly or increase over a period of time.

A healthy joint has movement that is free and comfortable. Ends of bones are encased by smooth cartilage, and are protected and lubricated by a synovial fluid inside the joint capsule. Normally healthy cartilage allows bones to glide over one another and helps absorb the shock of physical movement. In osteoarthritis the cartilage that covers the ends of the bones in the joints begins to break down and wear away, causing the bones to rub together, creating pain, swelling and loss of motion.1

Osteoarthritis (OA) is a type of arthritis that develops in the joints, the areas in the body where the bones are linked together. OA often involves the hips, knees, neck, lower back, or small joints of the hands. It is estimated that 1 in 11 Australians have osteoarthritis and 80% of these suffer from knee osteoarthritis.1

In an osteoarthritic joint, the synovial fluid loses its ability to effectively lubricate the joint. As the fluid thins, the joint rubs together, wearing away at the cartilage and bone. You may notice your knee becoming stiff and painful, and experience a general decrease in mobility in the joint. Affected joints may become enlarged and tender, affecting fine motor skills and leading to difficulty in performing everyday activities.1,5

Other causes of knee pain may include injuries, inflammation from wear and tear or other medical conditions.1


Viscosupplementation is a medical procedure during which lubricating fluid is injected into a joint. Also called hyaluronic acid injections, viscosupplementation is most commonly used to treat symptoms of knee osteoarthritis. Hyaluronic acid is a key component of the joint fluid in healthy joints, but is found in lower concentrations in osteoarthritic joints.

By adding hyaluronic acid to the existing joint fluid of an osteoarthritic knee, the goal is to:

  • Facilitate better knee movement
  • Reduce pain
  • Perhaps slow osteoarthritis progression

Typical candidates for viscosupplementation are people with knee osteoarthritis who have failed to improve with other non-surgical treatments.

How Viscosupplementation works

During viscosupplementation a small amount of hyaluronic acid, is injected directly into a joint capsule. Hyaluronic acid is a key component of the joint fluid. It gives the joint fluid its viscous, slippery quality, which does the following:

  • Enables the bones’ cartilage-covered surfaces to glide against each other, thereby reducing joint friction
  • Adds cushion to protect joints during impact (e.g. weight-bearing activity)

Joints affected by osteoarthritis typically have a lower concentration of hyaluronic acid in their joint fluid than healthy joints, and therefore less protection against joint friction and impact. Experts believe this further accelerates the joint degeneration process, setting in place a vicious cycle. As its name implies, viscosupplementation artificially supplements the joint fluid’s natural viscosity. By injecting a man-made hyaluronan into the knee, doctors hope to temporarily lubricate the knee joint, thereby decreasing pain improving function and  perhaps even slowing the degeneration process.3

The main goal of osteoarthritis treatment is to reduce pain to improve joint function. There are a variety of options depending on the severity of the disease and your doctor’s recommendation.


Exercise keeps limbs strong and active, and can extend the joint’s range of motion.

Weight Loss

By reducing pressure on the affected joint, further injury can be prevented and joint mobility increased.6

Pain Medication

Your doctor may suggest medicines for pain relief that can reduce pain and increase function/mobility for a limited time.

Viscosupplement Injections

Viscosupplements are a type of fluid that are injected directly into the knee to help lubricate and cushion the joint. By replacing lost synovial fluid, painless mobility can be restored to the joint for up to 6 months.2


If your knee pain is severe and other treatments have not provided relief, your doctor may discuss surgical options with you. Surgical treatment for osteoarthritis generally involves replacing some or all the joint.

Monovisc Syringe

Monovisc works by replacing lost hyaluronic acid (HA) back into the joint capsule.

In an osteoarthritic joint, joint fluid breaks down and becomes less effective at cushioning, lubricating and protecting the joint. Monovisc replenishes some of this natural supply, and can restore painless mobility and provide relief for up to 6 months.2,5

Monovisc is administered quickly and easily into the joint in a single injection, and has a meaningful reduction in knee pain within 2 weeks.2

High Dose

Monovisc is a high concentration viscosupplement. It is designed to supplement the reduced amount of natural HA in synovial fluid in osteoarthritic joints. The formulation of Monovisc allows for long-term relief of the symptoms of OA through lubrication and mechanical support.2,4

Single Injection

Unlike other HA injections Monovisc is administered in a single dose, lowering cost and reducing the number of visits to the doctor.4

Non-Animal Source

Monovisc is made from a highly purified, non-animal natural substance.4


How do I order Monovisc? Visit our Order Now section for more information on how to order Monovisc.

When should I consider Monovisc? If you have tried diet and exercise and still experience knee pain, talk with your doctor about their recommended treatment.

How is Monovisc given? Your physician will administer Monovisc in a single injection to the affected knee.4

How long does the treatment last? Monovisc has been shown to last up to 6 months.2

What happens after an injection with Monovisc? For the first 48 hours after an injection of Monovisc it’s recommended that you avoid any strenuous or high-impact activities.

Are there any side effects? Most people do not experience side effects with Monovisc.  Some people experience non-serious side effects including mild to moderate episodes of inflammation and discomfort which usually ease after a few days.4

Where do I go if I experience complications? Call your doctor or go to the emergency room immediately if any signs of infection appear (red, excessive drainage, fever) and always comply with your physician’s instructions.

Is the cost of Monovisc covered by insurance?  Treatment is not covered by Medicare, but it may be reimbursed via the Department of Veterans’ Affairs, Workers’ Compensation or your own private health insurance. Before treatment, please check with your private health insurance to see if you are eligible for any rebates.

Order Now

Please contact our Customer Service team on 1300 852 172 to order Monovisc. Have your name, address and contact number, as well as your practitioner’s name and contact information ready and credit card details to pay over the phone ready before you call.

Please note, you cannot order Monovisc without prior referral by one of our approved practitioners. Monovisc will be shipped directly to your practitioner before your next appointment.

If you have specific questions regarding your treatment, or other general medical concerns and questions, please contact your doctor. If you are looking for a health care practitioner in your local area that can talk to you about Monovisc, please contact the customer service team

For all other queries, comments and concerns, please use the form below.


  1. Australian Institute of health and Welfare. AIHW (online) Accessed 18 May 2018. https://www.aihw.gov.au/reports/arthritis-other-musculoskeletal-conditions/osteoarthritis/
  2. Petterson SC, Plancher KD. Single intra-articular injection of lightly cross-linked hyaluronic acid reduces knee pain in symptomatic knee osteoarthritis: a multicenter, double-blind, randomized, placebo-controlled trial. Knee Surgery, Sports Traumatology, Arthroscopy https://doi.org/10.1007/s00167-018-5114-0. Published 29 August 2018
  3. Arthritis-health (online) Accessed 18 May 2018 https://www.arthritis-health.com/treatment/injections/viscosupplementation-knee-osteoarthritis
  4. Monovisc. Instructions for Use
  5. Hui et al. Systems Biology approach to Synovial Joint lubrication in Health, injury and disease. Wiley Interdiscip Rev Syst Biol Med 4(1): 15-37 
  6. Johns Hopkins Arthritis Centre 2017. Osteoarthritis : Role of Body Weight in Osteoarthritis – Weight Management.  https://www.hopkinsarthritis.org/patient-corner/disease-management/role-of-body-weight-in-osteoarthritis

MONOVISC is a registered trademark of Anika Therapeutics, Inc., Bedford, MA 01730 U.S.A.
The information contained in this brochure applies exclusively to territories outside of USA.
AML 900-010/B